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Pharma partnerships

Stratify psychiatric trials by biology.

Psychiatric trials often fail because patients with the same diagnosis can have very different underlying biology. Our molecular signatures let drug developers see those differences, and build trials around them.

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Patients analysed
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Blinded studies
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Blood draw
Patient stratification

Same diagnosis. Different biology. Build trials on the difference.

Psychiatric clinical trials often fail because patients with the same diagnosis can have very different underlying biology, which makes it hard to identify who is most likely to respond to an investigational therapy. The same signatures that guide clinical decisions let pharmaceutical partners stratify patients by objective molecular profile.

Already in our data In our largest cohort (n = 850, Signature biobank), our models flag likely treatment-resistant patients and separate responders from non-responders by drug class. See the results →
Illustrative · one diagnosis, sorted into molecular profiles by a blood test
01 / Enrich

Enrich trials with the right patients

Select participants by molecular profile rather than symptoms alone, so each trial population reflects the biology a therapy is designed to act on.

02 / Detect

Improve signal detection

Biologically consistent cohorts make treatment effects easier to see and increase the likelihood of a successful clinical outcome.

03 / Deploy

Companion diagnostics

Following regulatory approval, the platform can be deployed as a companion diagnostic, helping clinicians identify the patients most likely to benefit from a specific therapy through a simple blood test.

How it works

From your cohort to a stratified trial.

Every partnership starts from your program's question. A typical collaboration moves through four steps.

01

Scope

Define the question together: the indication, the drug class and the outcome that matters for your program.

02

Profile

We run our molecular signatures on blood samples from your cohort, whether banked from earlier trials or collected at enrollment.

03

Stratify

Patients are grouped by molecular profile, and each group is analysed against treatment response and outcomes.

04

Deploy

Use the profiles to enrich future trials and, following regulatory approval, co-develop a companion diagnostic.

Partnerships

Let's talk about your next trial.

Whether you're planning a new psychiatric trial or revisiting one that missed its endpoint, we'd like to hear what you're working on.